ABSTRACT
Bronchial asthma is a highly prevalent disease and in most of the etiopathogenesis and symptomatology bronchial asthma can be co-related to that of Tamaka Shvasa. As the disease is originated from Pittasthana, Virechana Karma is indicated in the treatment of Shvasa Roga .In Charak Kalpasthana there are many Virechana Yogas are mentioned with different Kashay Kalpana. So, the present study is carried out to study efficacy of Virechana with Trivrutta in combination with other Drayas mentioned in Kalpasthana in the form of Leha Kalpana specifically indicated in Shvasa Roga. Aim: To study efficacy of Virechana karma with Trivrutta Leha Yoga in Tamaka Shvasa. Materials and Methods: Total 15 patients fulfilling the diagnostic criteria of Shvasa Roga were selected from OPD & IPD of Panchakarma Department. The Sign and symptoms mainly breathlessness, cough, ronchi were given scores depending on their severity. The patients were also assessed for Lung Function Test to determine pulmonary impairment. For the purpose of Virechana they were given Deepan Pachana with Trikatu Churna for 3 days then they were subjected to Snehapana with warm cow’s Ghee. The patients were given Abhyanga and Bashpaswedana for 4 days followed by Virechana with Trivrutta Leha Yoga and Sansarjana Krama. Follow up was done in an interval of 15 days for three times and scores were noted down before and after treatment. The scores were analyzed by using Wilcoxon Signed Rank Test for subjective parameters and Studant paired ‘t’ test for objective parameters. Result: The trial drug has shown statistically highly significant reduction in breathlessness, cough, rhonchi and significant changes in lung function tests. Conclusion: The formulation has proved its best purgative effect on bronchial Asthma and thus relives the symptoms of disease immediately. It has reduced frequency of episodes of breathlessness and severity of symptoms.
ABSTRACT
Background: Cirrhosis is a very common ailment in India mostly caused by alcoholism, viral hepatitis and malnutrition. The clinical picture of patients with cirrhosis is dominated by the classical complications such as ascites, bleeding from esophageal varices, portal hypertension and encephalopathy. Cardiovascular abnormalities have been reported by several investigators. Methods: It is a cross sectional study done on 60 patients admitted to NIMS Medical College, Jaipur between Jan. 2013 to Dec. 2014. USG of liver was done by GE Voluson promachine with probe frequency of 3.5 MHz and high frequency of 7-10 MHz for detection of cirrhosis and ascites with special reference to caudate lobe, portal vein and spleen. ANOVA with post hocTukey HSD was used for analysis of continuous variables whereas Chi-square test was used for nominal/ categorical variables. p value < 0.05 was taken as significant. Results: Diastolic dysfunction is measured by E/A ratio was prevalent LVED diameter, IV septal thickness, left ventricular posterior wall thickness were proportional to severity of liver cirrhosis. Electro physiologically, 38.33% patients of cirrhotic liver patients had prolonged QTc interval. Here, as far as cardiac abnormality were considered, we found QTc prolongation more in severe degree of cirrhosis MELD score III (7 out of 10) 70%, than moderate (40%) MELD score II and mild (20%) MELD score I of cardiac QTc prolongation. Conclusion: Diastolic dysfunction is a major criteria of cirrhotic cardiomyopathy which can be diagnosed by electro and echo cardiography